Family-Based Rare Variant Association Analysis: A Fast and Efficient Method of Multivariate Phenotype Association Analysis
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولRare Variant Analysis for Family-Based Design
Genome-wide association studies have been able to identify disease associations with many common variants; however most of the estimated genetic contribution explained by these variants appears to be very modest. Rare variants are thought to have larger effect sizes compared to common SNPs but effects of rare variants cannot be tested in the GWAS setting. Here we propose a novel method to test ...
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ژورنال
عنوان ژورنال: Genetic Epidemiology
سال: 2016
ISSN: 0741-0395
DOI: 10.1002/gepi.21985